Open AccessCatalytic Enantioselective Synthesis of β-Allenyl Boronic Esters by Conjunctive Cross-Coupling with Propargylic Carbonates
Author(s) -
Mark D. Aparece,
Weipeng Hu,
James P. Morken
Publication year - 2019
Publication title -
acs catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.898
H-Index - 198
ISSN - 2155-5435
DOI - 10.1021/acscatal.9b04453
Subject(s) - enantioselective synthesis , catalysis , chemistry , ligand (biochemistry) , combinatorial chemistry , reaction conditions , organic chemistry , biochemistry , receptor
Enantioselective conjunctive cross-coupling with propargylic carbonates affords (β-boryl allenes as the reaction product. The reaction is found to proceed through the intermediacy of dimethoxyboronate complexes that are generated in situ by a strain-induced ligand exchange reaction.