Substrate Binding Induces Conformational Changes in a Class A β-lactamase That Prime It for Catalysis
Author(s) -
Patricia S. Langan,
Venu Gopal Vandavasi,
Connor J. Cooper,
Kevin L. Weiss,
Stephan L. Ginell,
Jerry M. Parks,
Leighton Coates
Publication year - 2018
Publication title -
acs catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.898
H-Index - 198
ISSN - 2155-5435
DOI - 10.1021/acscatal.7b04114
Subject(s) - chemistry , active site , stereochemistry , nucleophile , catalysis , acylation , enzyme catalysis , substrate (aquarium) , binding site , combinatorial chemistry , biochemistry , biology , ecology
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