
Enantioselective Flow Synthesis of Rolipram Enabled by a Telescoped Asymmetric Conjugate Addition–Oxidative Aldehyde Esterification Sequence Using in Situ-Generated Persulfuric Acid as Oxidant
Author(s) -
Bence S. Nagy,
Patricia Llanes,
Miquel À. Pericàs,
C. Oliver Kappe,
Sándor B. Ötvös
Publication year - 2022
Publication title -
organic letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.94
H-Index - 239
eISSN - 1523-7060
pISSN - 1523-7052
DOI - 10.1021/acs.orglett.1c04300
Subject(s) - chemistry , enantioselective synthesis , aldehyde , conjugate , rolipram , oxidative phosphorylation , combinatorial chemistry , organic chemistry , catalysis , enzyme , biochemistry , mathematical analysis , mathematics , phosphodiesterase