Ru3(CO)12-Catalyzed Reaction of 1,6-Diynes, Carbon Monoxide, and Water via the Reductive Coupling of Carbon Monoxide | Zendy

Cathleen M. Crudden | Zendy; Yuuki Maekawa | Zendy; Joshua J. Clarke | Zendy; Tomohide Ida | Zendy; Yoshiya Fukumoto | Zendy; Naoto Chatani | Zendy; Shinji Murai | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Ru₃(CO)₁₂-Catalyzed Reaction of 1,6-Diynes, Carbon Monoxide, and Water via the Reductive Coupling of Carbon Monoxide

Author(s) -

Cathleen M. Crudden,

Yuuki Maekawa,

Joshua J. Clarke,

Tomohide Ida,

Yoshiya Fukumoto,

Naoto Chatani,

Shinji Murai

Publication year - 2020

Publication title -

organic letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.94

H-Index - 239

eISSN - 1523-7060

pISSN - 1523-7052

DOI - 10.1021/acs.orglett.0c02349

Subject(s) - carbon monoxide , chemistry , catalysis , ruthenium , water gas shift reaction , hydride , cycloaddition , molecule , coupling reaction , diol , photochemistry , organic chemistry , hydrogen

We report the ruthenium-catalyzed cyclization of 1,6-diynes with two molecules of carbon monoxide and water to give a variety of catechols. This reaction likely proceeds through the intermediacy of the water-gas shift reaction to generate an yne-diol-type intermediate followed by a [4 + 2] cycloaddition with 1,6-diynes. The reaction requires no external reductants or hydride sources and provides a novel and valuable method for the synthesis of a variety of catechols.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research