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Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction
Author(s) -
Jürgen Ramharter,
Michael Kulhanek,
Maike Dettling,
Gerhard Gmaschitz,
Jale KarolyiOezguer,
Harald Weinstabl,
Andreas Gollner
Publication year - 2022
Publication title -
organic process research and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 109
eISSN - 1520-586X
pISSN - 1083-6160
DOI - 10.1021/acs.oprd.2c00192
Subject(s) - stereocenter , cycloaddition , chemistry , combinatorial chemistry , ring (chemistry) , 1,3 dipolar cycloaddition , stereochemistry , computational chemistry , organic chemistry , catalysis , enantioselective synthesis

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