Open AccessPhenol Derivatives as Coupling Partners with Alkylsilicates in Photoredox/Nickel Dual Catalysis
Author(s) -
Niki R. Patel,
Gary A. Molander
Publication year - 2016
Publication title -
journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.2
H-Index - 228
eISSN - 1520-6904
pISSN - 0022-3263
DOI - 10.1021/acs.joc.6b00800
Subject(s) - chemistry , nickel , transmetalation , catalysis , electrophile , phenol , coupling (piping) , aryl , photochemistry , photoredox catalysis , dual role , combinatorial chemistry , organic chemistry , photocatalysis , alkyl , mechanical engineering , engineering
Photoredox/nickel dual catalysis via single electron transmetalation allows coupling of Csp(3)-Csp(2) hybridized centers under mild conditions. A procedure for the coupling of electron-deficient aryl triflates, -tosylates, and -mesylates with alkylbis(catecholato)silicates is presented. This method represents the first example of the use of phenol derivatives as electrophilic coupling partners in photoredox/nickel dual catalysis.