Open AccessN-Aminopyridinium Ylide-Directed, Copper-Promoted Chalcogenation of Arene C–H Bonds
Author(s) -
Hanh Nho Nguyen,
Olafs Daugulis
Publication year - 2020
Publication title -
the journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.2
H-Index - 228
eISSN - 1520-6904
pISSN - 0022-3263
DOI - 10.1021/acs.joc.0c01757
Subject(s) - chemistry , ylide , copper , alkyl , medicinal chemistry , aryl , solvent , polymer chemistry , organic chemistry
N -Aminopyridinium ylide-directing group is employed for copper-promoted chalcogenation of sp 2 C-H bonds with aryl and alkyl disulfides as well as diphenyl diselenide. Reactions proceed in hexafluoroisopropanol (HFIP) solvent at elevated temperatures and are promoted by copper(II) acetate.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom