Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analogue with Enhanced Stability
Author(s) -
Nan Zheng,
Prasoona Karra,
Michael A. VandenBerg,
Jin Hwan Kim,
Matthew J. Webber,
William L. Holland,
Danny HungChieh Chou
Publication year - 2019
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.9b01589
Subject(s) - chemistry , insulin , thioacetal , methylene , diabetes mellitus , insulin resistance , combinatorial chemistry , medicine , endocrinology , stereochemistry , organic chemistry , acetal
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