Open AccessDesign, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
Author(s) -
Zdeněk Vavřina,
Pavla Perlíková,
Nemanja Milisavljević,
Florian Chevrier,
Miroslav Smola,
J. Nicholas B. Smith,
Milan Dejmek,
Vojtěch Havlíček,
Miloš Budĕšı́nský,
Radek Liboska,
Lenka Vaneková,
J. Brynda,
Evžen Bouřa,
P. Řezačová,
Michal Hocek,
Gabriel Birkuš
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c01305
Subject(s) - chemistry , stimulator of interferon genes , sting , ligand (biochemistry) , stacking , stereochemistry , moiety , combinatorial chemistry , receptor , biochemistry , innate immune system , engineering , aerospace engineering , organic chemistry