Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists | Zendy

Zdeněk Vavřina | Zendy; Pavla Perlíková | Zendy; Nemanja Milisavljević | Zendy; Florian Chevrier | Zendy; Miroslav Smola | Zendy; Joshua Smith | Zendy; Milan Dejmek | Zendy; Vojtěch Havlíček | Zendy; Miloš Buděšı́nský | Zendy; Radek Liboska | Zendy; Lenka Vaneková | Zendy; J. Brynda | Zendy; Evžen Bouřa | Zendy; Pavlína Řezáčová | Zendy; Michal Hocek | Zendy; Gabriel Birkuš | Zendy

Open Access

Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists

Author(s) -

Zdeněk Vavřina,

Pavla Perlíková,

Nemanja Milisavljević,

Florian Chevrier,

Miroslav Smola,

Joshua Smith,

Milan Dejmek,

Vojtěch Havlíček,

Miloš Buděšı́nský,

Radek Liboska,

Lenka Vaneková,

J. Brynda,

Evžen Bouřa,

Pavlína Řezáčová,

Michal Hocek,

Gabriel Birkuš

Publication year - 2022

Publication title -

journal of medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.01

H-Index - 261

eISSN - 1520-4804

pISSN - 0022-2623

DOI - 10.1021/acs.jmedchem.2c01305

Subject(s) - chemistry , stimulator of interferon genes , sting , ligand (biochemistry) , stacking , stereochemistry , moiety , combinatorial chemistry , receptor , biochemistry , innate immune system , engineering , aerospace engineering , organic chemistry

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