Large-Scale Ligand Perturbations of the Protein Conformational Landscape Reveal State-Specific Interaction Hotspots
Author(s) -
Timothy R. Stachowski,
Marcus Fischer
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c00708
Subject(s) - chemistry , docking (animal) , hsp90 , ligand (biochemistry) , computational biology , binding site , chaperone (clinical) , protein data bank , plasma protein binding , protein structure , biophysics , heat shock protein , biochemistry , biology , medicine , nursing , receptor , pathology , gene
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