Open AccessSelective C9orf72 G-Quadruplex-Binding Small Molecules Ameliorate Pathological Signatures of ALS/FTD Models
Author(s) -
Aifang Cheng,
Changdong Liu,
Wenkang Ye,
Duli Huang,
Weiyi She,
Xin Liu,
Chun Po Fung,
Naining Xu,
Monica Ching Suen,
Wei Ye,
Herman Ho Yung Sung,
Ian D. Williams,
Guang Zhu,
PeiYuan Qian
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c00654
Subject(s) - chemistry , c9orf72 , frontotemporal dementia , rna , amyotrophic lateral sclerosis , trinucleotide repeat expansion , stereochemistry , biochemistry , microbiology and biotechnology , gene , dementia , biology , medicine , allele , disease
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