Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors | Zendy

Sandra Codony | Zendy; José M. Entrena | Zendy; Carla CalvóTusell | Zendy; Beatrice Jora | Zendy; Rafael GonzálezCano | Zendy; Sílvia Osuna | Zendy; Rubén Corpas | Zendy; Christophe Morisseau | Zendy; Belen Pérez | Zendy; Marta BarniolXicota | Zendy; Christian GriñánFerré | Zendy; Concepción Pérez | Zendy; Marı́a Isabel Rodrı́guez-Franco | Zendy; Antón L. Martínez | Zendy; Marı́a Isabel Loza | Zendy; Mercé Pallás | Zendy; Steven H. L. Verhelst | Zendy; Coral Sanfeliu | Zendy; Ferran Feixas | Zendy; Bruce D. Hammock | Zendy; José Brea | Zendy; Enrique J. Cobos | Zendy; Santiago Vázquez | Zendy

Open Access

Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors

Author(s) -

Sandra Codony,

José M. Entrena,

Carla CalvóTusell,

Beatrice Jora,

Rafael GonzálezCano,

Sílvia Osuna,

Rubén Corpas,

Christophe Morisseau,

Belen Pérez,

Marta BarniolXicota,

Christian GriñánFerré,

Concepción Pérez,

Marı́a Isabel Rodrı́guez-Franco,

Antón L. Martínez,

Marı́a Isabel Loza,

Mercé Pallás,

Steven H. L. Verhelst,

Coral Sanfeliu,

Ferran Feixas,

Bruce D. Hammock,

José Brea,

Enrique J. Cobos,

Santiago Vázquez

Publication year - 2022

Publication title -

journal of medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.01

H-Index - 261

eISSN - 1520-4804

pISSN - 0022-2623

DOI - 10.1021/acs.jmedchem.2c00515

Subject(s) - in vivo , epoxide hydrolase 2 , chemistry , pharmacology , pharmacokinetics , allodynia , analgesic , in vitro , epoxide hydrolase , microsomal epoxide hydrolase , hyperalgesia , microsome , biochemistry , enzyme , medicine , nociception , receptor , biology , microbiology and biotechnology

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