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Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4
Author(s) -
Chetan K. Chana,
Pierre Maisonneuve,
Ganna Posternak,
Nicolas G.A. Grinberg,
Juline Poirson,
Samara Mishelle Ona,
Derek F. Ceccarelli,
P. Mäder,
Daniel J. StCyr,
Victor P.T. Pau,
Igor Kurinov,
Xiaojing Tang,
Dongjing Deng,
Weiren Cui,
Wenji Su,
Letian Kuai,
Richard Söll,
Mike Tyers,
Hannes Röst,
Robert A. Batey,
Mikko Taipale,
AnneClaude Gingras,
Frank Sicheri
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c00509
Subject(s) - chemistry , ubiquitin ligase , protein subunit , small molecule , dna ligase , stereochemistry , in vitro , ubiquitin , molecule , effector , ubiquitin protein ligases , biochemistry , biophysics , dna , gene , biology , organic chemistry

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