Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease | Zendy

Chamandi S. Dampalla | Zendy; Athri D. Rathnayake | Zendy; Anushka C. Galasiti Kankanamalage | Zendy; Yunjeong Kim | Zendy; Krishani Dinali Perera | Zendy; Harry Nhat Nguyen | Zendy; Matthew J. Miller | Zendy; Trent K. Madden | Zendy; Hunter R. Picard | Zendy; Hayden A. Thurman | Zendy; M.M. Kashipathy | Zendy; Lijun Liu | Zendy; K.P. Battaile | Zendy; Scott Lovell | Zendy; KyeongOk Chang | Zendy; William C. Groutas | Zendy

Open Access

Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease

Author(s) -

Chamandi S. Dampalla,

Athri D. Rathnayake,

Anushka C. Galasiti Kankanamalage,

Yunjeong Kim,

Krishani Dinali Perera,

Harry Nhat Nguyen,

Matthew J. Miller,

Trent K. Madden,

Hunter R. Picard,

Hayden A. Thurman,

M.M. Kashipathy,

Lijun Liu,

K.P. Battaile,

Scott Lovell,

KyeongOk Chang,

William C. Groutas

Publication year - 2022

Publication title -

journal of medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.01

H-Index - 261

eISSN - 1520-4804

pISSN - 0022-2623

DOI - 10.1021/acs.jmedchem.2c00224

Subject(s) - chemistry , protease , coronavirus , covid-19 , potency , drug discovery , structure–activity relationship , chemical space , viral replication , severe acute respiratory syndrome coronavirus , virology , enzyme , computational biology , virus , biochemistry , in vitro , biology , medicine , disease , pathology , infectious disease (medical specialty) , outbreak

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