Open AccessStructure–Activity Relationships of 8-Hydroxyquinoline-Derived Mannich Bases with Tertiary Amines Targeting Multidrug-Resistant Cancer
Author(s) -
Veronika F.S. Pape,
Roberta Palkó,
Szilárd Tóth,
Miklós J. Szabó,
Judit Sessler,
György Dormán,
Éva A. Enyedy,
Tibor Soós,
István Szatmári,
Gergely Szakács
Publication year - 2022
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.2c00076
Subject(s) - chemistry , mannich base , moiety , multiple drug resistance , combinatorial chemistry , 8 hydroxyquinoline , cytotoxicity , protonation , stereochemistry , cancer cell , chelation , chemical space , cancer , pharmacology , in vitro , biochemistry , organic chemistry , drug discovery , antibiotics , medicine , ion
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