Open AccessDevelopment of 3-(4-Chlorophenyl)-1-(phenethyl)urea Analogues as Allosteric Modulators of the Cannabinoid Type-1 Receptor: RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior
Author(s) -
Thuy Nguyen,
Thomas F. Gamage,
David B. Finlay,
Ann M. Decker,
Tiffany L. Langston,
Daniel G. Barrus,
Michelle Glass,
JunXu Li,
Terry Kenakin,
Yanan Zhang
Publication year - 2021
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.1c01432
Subject(s) - chemistry , cannabinoid receptor , potency , pharmacology , cannabinoid , allosteric regulation , pharmacokinetics , lipophilicity , receptor , stereochemistry , biochemistry , in vitro , agonist , medicine
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