Open Access4-Methyl-1,2,3-Triazoles as N-Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity
Author(s) -
Huarui Cui,
Angela S. Carlson,
Mary A. Schleiff,
Anand Divakaran,
Jorden A. Johnson,
Caroline R. Buchholz,
Huda Zahid,
Nora R. Vail,
Ke Shi,
Hideki Aihara,
Daniel A. Harki,
Grover P. Miller,
Joseph J. Topczewski,
William C. K. Pomerantz
Publication year - 2021
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.1c00933
Subject(s) - bromodomain , chemistry , brd4 , acetylation , lysine , histone , transcription factor , transcription (linguistics) , biochemistry , amino acid , gene , linguistics , philosophy
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