Open AccessDiscovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91
Author(s) -
Maha Hanafi,
Xinde Chen,
Nouri Neamati
Publication year - 2021
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.0c01897
Subject(s) - ubiquitin ligase , ubiquitin , chemistry , stat3 , proteasome , cytotoxicity , dna ligase , protein degradation , proteolysis , microbiology and biotechnology , signal transduction , cancer research , biochemistry , biology , in vitro , enzyme , gene
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