Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity | Zendy

Paul T. Marcyk | Zendy; Emmanuelle V. LeBlanc | Zendy; D.A. Kuntz | Zendy; Alice Xue | Zendy; Francisco Ortiz | Zendy; Richard Trilles | Zendy; Stephen Bengtson | Zendy; Tristan M. G. Kenney | Zendy; David S. Huang | Zendy; Nicole Robbins | Zendy; Noelle S. Williams | Zendy; Damian J. Krysan | Zendy; Gilbert G. Privé | Zendy; Luke Whitesell | Zendy; Leah E. Cowen | Zendy; Lauren E. Brown | Zendy

Open Access

Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity

Author(s) -

Paul T. Marcyk,

Emmanuelle V. LeBlanc,

D.A. Kuntz,

Alice Xue,

Francisco Ortiz,

Richard Trilles,

Stephen Bengtson,

Tristan M. G. Kenney,

David S. Huang,

Nicole Robbins,

Noelle S. Williams,

Damian J. Krysan,

Gilbert G. Privé,

Luke Whitesell,

Leah E. Cowen,

Lauren E. Brown

Publication year - 2021

Publication title -

journal of medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.01

H-Index - 261

eISSN - 1520-4804

pISSN - 0022-2623

DOI - 10.1021/acs.jmedchem.0c01777

Subject(s) - cryptococcus neoformans , hsp90 , candida albicans , gene isoform , chemistry , hsp90 inhibitor , biochemistry , microbiology and biotechnology , biology , heat shock protein , gene

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