Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria | Zendy

Sreekanth Kokkonda | Zendy; Xiaoyi Deng | Zendy; Karen L. White | Zendy; Farah El Mazouni | Zendy; John White | Zendy; David M. Shackleford | Zendy; Kasiram Katneni | Zendy; Francis C. K. Chiu | Zendy; Helena Barker | Zendy; Jenna McLaren | Zendy; Elly Crighton | Zendy; Gong Chen | Zendy; Íñigo AnguloBarturen | Zendy; Marı́a Belén Jiménez-Dı́az | Zendy; Santiago Ferrer | Zendy; Leticia Huertas-Valentín | Zendy; María Santos Martínez | Zendy; María José Lafuente-Monasterio | Zendy; Rajesh Chittimalla | Zendy; Shatrughan P. Shahi | Zendy; Sergio Wittlin | Zendy; David Waterson | Zendy; Jeremy N. Burrows | Zendy; Dave Matthews | Zendy; D.R. Tomchick | Zendy; Pradipsinh K. Rathod | Zendy; Michael Palmer | Zendy; Susan A. Charman | Zendy; Margaret A. Phillips | Zendy

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Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria

Author(s) -

Sreekanth Kokkonda,

Xiaoyi Deng,

Karen L. White,

Farah El Mazouni,

John White,

David M. Shackleford,

Kasiram Katneni,

Francis C. K. Chiu,

Helena Barker,

Jenna McLaren,

Elly Crighton,

Gong Chen,

Íñigo AnguloBarturen,

Marı́a Belén Jiménez-Dı́az,

Santiago Ferrer,

Leticia Huertas-Valentín,

María Santos Martínez,

María José Lafuente-Monasterio,

Rajesh Chittimalla,

Shatrughan P. Shahi,

Sergio Wittlin,

David Waterson,

Jeremy N. Burrows,

Dave Matthews,

D.R. Tomchick,

Pradipsinh K. Rathod,

Michael Palmer,

Susan A. Charman,

Margaret A. Phillips

Publication year - 2020

Publication title -

journal of medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.01

H-Index - 261

eISSN - 1520-4804

pISSN - 0022-2623

DOI - 10.1021/acs.jmedchem.0c00311

Subject(s) - chemistry , malaria , series (stratigraphy) , dihydroorotate dehydrogenase , pyrrole , pharmacology , biochemistry , combinatorial chemistry , stereochemistry , enzyme , organic chemistry , immunology , medicine , biology , paleontology

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