Open AccessTruncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A3 Adenosine Receptors: Affinity Enhancement by N6-(2-Phenylethyl) Substitution
Author(s) -
Dilip K. Tosh,
Veronica Salmaso,
Harsha Rao,
Amelia Bitant,
Courtney Fisher,
David I. Lieberman,
Helmut Vorbrüggen,
Marc L. Reitman,
Oksana Gavrilova,
ZhanGuo Gao,
John A. Auchampach,
Kenneth A. Jacobson
Publication year - 2020
Publication title -
journal of medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.01
H-Index - 261
eISSN - 1520-4804
pISSN - 0022-2623
DOI - 10.1021/acs.jmedchem.0c00235
Subject(s) - chemistry , partial agonist , agonist , stereochemistry , adenosine , adenosine receptor , antagonist , receptor , in vitro , in vivo , homology modeling , biochemistry , enzyme , microbiology and biotechnology , biology
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