Comparing Metal–Halide and −Oxygen Adducts in Oxidative C/O–H Activation: AuIII–Cl versus AuIII–OH | Zendy

Marta Lovisari | Zendy; Robert Gericke | Zendy; Brendan Twamley | Zendy; Aidan R. McDonald | Zendy

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Comparing Metal–Halide and −Oxygen Adducts in Oxidative C/O–H Activation: Au^III–Cl versus Au^III–OH

Author(s) -

Marta Lovisari,

Robert Gericke,

Brendan Twamley,

Aidan R. McDonald

Publication year - 2021

Publication title -

inorganic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.348

H-Index - 233

eISSN - 1520-510X

pISSN - 0020-1669

DOI - 10.1021/acs.inorgchem.1c02222

Subject(s) - chemistry , adduct , halide , metal , ligand (biochemistry) , oxygen , oxidative addition , medicinal chemistry , oxygen atom , metal halides , terpyridine , inorganic chemistry , photochemistry , molecule , catalysis , organic chemistry , biochemistry , receptor

High-valent metal-halides have come to prominence as highly effective oxidants. A direct comparison of their efficacy against that of traditional metal-oxygen adducts is needed. [Au III (Cl)(terpy)](ClO 4 ) 2 ( 1 ; terpy = 2,2':6',2-terpyridine) readily oxidized substrates bearing O-H and C-H bonds via a hydrogen atom transfer mechanism. A direct comparison with [Au III (OH)(terpy)](ClO 4 ) 2 ( 2 ) showed that 1 was a kinetically superior oxidant with respect to 2 for all substrates tested. We ascribe this to the greater thermodynamic driving force imbued by the Cl ligand versus the OH ligand.

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