Water Dynamics in the Hydration Shells of Biomolecules | Zendy

Damien Laage | Zendy; Thomas Elsaesser | Zendy; James T. Hynes | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Water Dynamics in the Hydration Shells of Biomolecules

Author(s) -

Damien Laage,

Thomas Elsaesser,

James T. Hynes

Publication year - 2017

Publication title -

chemical reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 20.528

H-Index - 700

eISSN - 1520-6890

pISSN - 0009-2665

DOI - 10.1021/acs.chemrev.6b00765

Subject(s) - biomolecule , chemistry , chemical physics , microsecond , femtosecond , molecular dynamics , molecule , relaxation (psychology) , nanotechnology , computational chemistry , physics , materials science , psychology , social psychology , laser , biochemistry , organic chemistry , astronomy , optics

The structure and function of biomolecules are strongly influenced by their hydration shells. Structural fluctuations and molecular excitations of hydrating water molecules cover a broad range in space and time, from individual water molecules to larger pools and from femtosecond to microsecond time scales. Recent progress in theory and molecular dynamics simulations as well as in ultrafast vibrational spectroscopy has led to new and detailed insight into fluctuations of water structure, elementary water motions, electric fields at hydrated biointerfaces, and processes of vibrational relaxation and energy dissipation. Here, we review recent advances in both theory and experiment, focusing on hydrated DNA, proteins, and phospholipids, and compare dynamics in the hydration shells to bulk water.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research