Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications | Zendy

Johan R. Johansson | Zendy; Tamás BekeSomfai | Zendy; Anna Said Stålsmeden | Zendy; Nina Kann | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications

Author(s) -

Johan R. Johansson,

Tamás BekeSomfai,

Anna Said Stålsmeden,

Nina Kann

Publication year - 2016

Publication title -

chemical reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 20.528

H-Index - 700

eISSN - 1520-6890

pISSN - 0009-2665

DOI - 10.1021/acs.chemrev.6b00466

Subject(s) - chemistry , cycloaddition , alkyne , ruthenium , azide , catalysis , combinatorial chemistry , scope (computer science) , supramolecular chemistry , click chemistry , reaction mechanism , organic chemistry , molecule , computer science , programming language

The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer. The RuAAC reaction has quickly found its way into the organic chemistry toolbox and found applications in many different areas, such as medicinal chemistry, polymer synthesis, organocatalysis, supramolecular chemistry, and the construction of electronic devices. This Review discusses the mechanism, scope, and applications of the RuAAC reaction, covering the literature from the last 10 years.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research