Open AccessInterindividual Variability in Cytochrome P450 3A and 1A Activity Influences Sunitinib Metabolism and Bioactivation
Author(s) -
Elizabeth A. Burnham,
Arsany A. Abouda,
Jennifer E. Bissada,
Dasean T. Nardone-White,
Jessica L. Beers,
JongHwa Lee,
Matthew J. Vergne,
Klarissa D. Jackson
Publication year - 2022
Publication title -
chemical research in toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 156
eISSN - 1520-5010
pISSN - 0893-228X
DOI - 10.1021/acs.chemrestox.1c00426
Subject(s) - cytochrome p450 , sunitinib , drug metabolism , chemistry , cyp2d6 , metabolism , cyp2b6 , cyp2a6 , cytochrome , pharmacology , cyp1a2 , biology , biochemistry , enzyme , genetics , cancer
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