Novel Δ8-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals | Zendy

Jiries Meehan-Atrash | Zendy; Irfan Rahman | Zendy

Open Access

Novel Δ⁸-Tetrahydrocannabinol Vaporizers Contain Unlabeled Adulterants, Unintended Byproducts of Chemical Synthesis, and Heavy Metals

Author(s) -

Jiries Meehan-Atrash,

Irfan Rahman

Publication year - 2021

Publication title -

chemical research in toxicology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.031

H-Index - 156

eISSN - 1520-5010

pISSN - 0893-228X

DOI - 10.1021/acs.chemrestox.1c00388

Subject(s) - chemistry , cannabis , heavy metals , tetrahydrocannabinol , environmental chemistry , radiochemistry , nuclear chemistry , chromatography , organic chemistry , cannabinoid , biochemistry , medicine , receptor , psychiatry

Cannabis e-cigarettes containing Δ 8 -tetrahydrocannabinol (Δ 8 -THC) produced synthetically from hemp-derived cannabidiol (CBD) have recently risen in popularity as a legal means of cannabis consumption, but questions surrounding purity and unlabeled additives have created doubts of their safety. Herein, NMR, GC-MS, and ICP-MS were used to analyze major components of 27 products from 10 brands, and it was determined none of these had accurate Δ 8 -THC labeling, 11 had unlabeled cutting agents, and all contained reaction side-products including olivetol, Δ 4(8) - iso -tetrahydrocannabinol, 9-ethoxyhexahydrocannabinol, Δ 9 -tetrahydrocannabinol (Δ 9 -THC), heavy metals, and a novel previously undescribed cannabinoid, iso -tetrahydrocannabifuran.

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