Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening
Author(s) -
Vishnu Mini Sasi,
Sven Ullrich,
Jennifer Ton,
Sarah E. Fry,
Jason JohansenLeete,
Richard J. Payne,
Christoph Nitsche,
Colin J. Jackson
Publication year - 2022
Publication title -
biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.43
H-Index - 253
eISSN - 1520-4995
pISSN - 0006-2960
DOI - 10.1021/acs.biochem.2c00489
Subject(s) - in silico , protease , protease inhibitor (pharmacology) , drug resistance , biology , mutation , virology , peptide , covid-19 , resistance mutation , virus , computational biology , genetics , enzyme , biochemistry , gene , infectious disease (medical specialty) , medicine , reverse transcriptase , viral load , disease , pathology , antiretroviral therapy , rna
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