Tissue Papers: Leveraging Paper-Based Microfluidics for the Next Generation of 3D Tissue Models | Zendy

Sabrina M. Cramer | Zendy; Tyler S. Larson | Zendy; Matthew R. Lockett | Zendy

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Tissue Papers: Leveraging Paper-Based Microfluidics for the Next Generation of 3D Tissue Models

Author(s) -

Sabrina M. Cramer,

Tyler S. Larson,

Matthew R. Lockett

Publication year - 2019

Publication title -

analytical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.117

H-Index - 332

eISSN - 1520-6882

pISSN - 0003-2700

DOI - 10.1021/acs.analchem.9b02102

Subject(s) - microfluidics , chemistry , plant tissue , tissue engineering , nanotechnology , biochemical engineering , computational biology , biomedical engineering , biology , engineering , materials science , botany

Paper-based scaffolds support the three-dimensional culture of mammalian cells in tissue-like environments. These Tissue Papers, a name that highlights the use of materials obtained from (plant) tissue to generate newly functioning (human) tissue structures, are a promising analytical tool to quantify cellular responses in physiologically relevant extracellular gradients and coculture architectures. Here, we highlight current examples of Tissue Papers, commonly used methods of analysis, and current measurement challenges.

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