Open AccessProtein Unfolding in Freeze Frames: Intermediate States are Revealed by Variable-Temperature Ion Mobility–Mass Spectrometry
Author(s) -
Jakub Ujma,
Jacquelyn R. Jhingree,
Emma Norgate,
Rosie Upton,
Xudong Wang,
Florian Benoit,
Bruno Bellina,
Perdita E. Barran
Publication year - 2022
Publication title -
analytical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.117
H-Index - 332
eISSN - 1520-6882
pISSN - 0003-2700
DOI - 10.1021/acs.analchem.2c03066
Subject(s) - chemistry , ion mobility spectrometry , mass spectrometry , lysozyme , conformational isomerism , context (archaeology) , protein structure , protein folding , ion , crystallography , denaturation (fissile materials) , chemical physics , molecule , chromatography , organic chemistry , biochemistry , paleontology , nuclear chemistry , biology
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