Open AccessSubjective Cognitive Decline and its Relation to Verbal Memory and Sex in Cognitively Unimpaired Individuals from a Colombian Cohort with Autosomal-Dominant Alzheimer’s Disease
Author(s) -
Jean-Louis Martinez,
Enmanuelle PardillaDelgado,
Edmarie Guzmán-Vélez,
Clara VilaCastelar,
Rebecca E. Amariglio,
Jennifer R. Gatchel,
Daniel Camilo Aguirre–Acevedo,
Yamile Bocanegra,
Ana Baena,
Eliana Henao,
Victoria Tirado,
Claudia Muñoz,
Margarita GiraldoChica,
Francisco Lopera,
Yakeel T. Quiroz
Publication year - 2021
Publication title -
journal of the international neuropsychological society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.074
H-Index - 127
eISSN - 1469-7661
pISSN - 1355-6177
DOI - 10.1017/s1355617721000801
Subject(s) - dementia , disease , recall , verbal memory , cognition , psychology , cognitive decline , medicine , clinical psychology , psychiatry , cognitive psychology
Subjective Cognitive Decline (SCD) may be an early indicator of risk for Alzheimer's disease (AD). Findings regarding sex differences in SCD are inconsistent. Studying sex differences in SCD within cognitively unimpaired individuals with autosomal-dominant AD (ADAD), who will develop dementia, may inform sex-related SCD variations in preclinical AD. We examined sex differences in SCD within cognitively unimpaired mutation carriers from the world's largest ADAD kindred and sex differences in the relationship between SCD and memory performance.