Open AccessParecoxib vs. lornoxicam in the treatment of postoperative pain after laparoscopic cholecystectomy: a prospective randomized placebo-controlled trial
Author(s) -
Artemisia Papadima,
Emmanuel Lagoudianakis,
Pantelis Antonakis,
Michael Pattas,
F. Kremastinou,
Vaggelogiannis Katergiannakis,
Andreas Manouras,
L. Georgiou
Publication year - 2007
Publication title -
european journal of anaesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 76
eISSN - 1365-2346
pISSN - 0265-0215
DOI - 10.1017/s0265021506001293
Subject(s) - lornoxicam , medicine , parecoxib , visual analogue scale , placebo , anesthesia , randomized controlled trial , adverse effect , cholecystectomy , laparoscopic cholecystectomy , analgesic , surgery , pathology , alternative medicine
Non-steroidal anti-inflammatory drugs are considered as an effective treatment of postoperative pain after laparoscopic cholecystectomy. COX-2 inhibitors are newer drugs having less adverse effects. Data supporting their efficacy postoperatively in comparison to older non-steroidal anti-inflammatory drugs are scarce. Our study is a prospective, randomized, double-blinded, placebo-controlled trial comparing the efficacy of lornoxicam vs. parecoxib for the management of pain after laparoscopic cholecystectomy.