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A simple method for computer quantification of stage REM eye movement potentials
Author(s) -
Tan Xin,
Campbell Ian Glenn,
Feinberg Irwin
Publication year - 2001
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1017/s0048577201000816
Subject(s) - eye movement , fast fourier transform , rapid eye movement sleep , movement (music) , electroencephalography , sleep (system call) , computer mouse , electrooculography , psychology , artificial intelligence , computer science , pattern recognition (psychology) , computer vision , audiology , neuroscience , algorithm , computer hardware , medicine , philosophy , operating system , aesthetics
We describe a simple method for computer quantification of eye movement (EM) potentials during REM sleep. This method can be applied by investigators using either period‐amplitude (PA) or Fast Fourier Transform (FFT) spectral EEG analysis without special hardware or computer programming. It provides good correlations with visual ratings of EM in baseline sleep and after administration of GABAergic hypnotics. We present baseline data for both PA and FFT measures for 16 normal subjects, studied for 5 consecutive nights. Both visually rated and computer‐measured EM density (EMD) showed high night‐to‐night correlations across baseline and drug nights and the computer measures detected the EMD suppression that is produced by GABAergic drugs. Measurement of EM in addition to stage REM provides biologically significant information and application of this simple computer method, which does not require pattern recognition algorithms or special hardware, could provide reliable data that can be compared across laboratories.