Open AccessThe Perils of Multiplex Gastrointestinal Pathogen Panels: Pseudo-outbreaks of Salmonellae and Entamoeba histolytica in Immunocompromised Hosts
Author(s) -
Elizabeth Robilotti,
Eleanor A. Powell,
Shauna Usiak,
Ying Taur,
N. Esther Babady,
Mini Kamboj
Publication year - 2018
Publication title -
infection control and hospital epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.243
H-Index - 138
eISSN - 1559-6834
pISSN - 0899-823X
DOI - 10.1017/ice.2018.95
Subject(s) - entamoeba histolytica , pathogen , transmission (telecommunications) , microbiology and biotechnology , outbreak , virology , multiplex , biology , multiplex polymerase chain reaction , polymerase chain reaction , gene , bioinformatics , genetics , electrical engineering , engineering
Two distinct clusters of gastroenteritis due to Salmonellae and Entamoeba histolytica (EH) were identified using a multiplex gastrointestinal pathogen panel (GPP) at a tertiary-care cancer center. Despite temporo-spatial overlap, our investigation did not corroborate transmission or true infection. In clinical practice, GPPs may render false-positive results.Infect Control Hosp Epidemiol 2018;867-870.