Open AccessRare Presentation of Prostate Cancer Mimicking Malignant Lymphoma with Generalized Lymphadenopathy
Author(s) -
Yu-Fen Tsai,
ShihFeng Cho,
ChunChieh Wu,
Ta-Chih Liu
Publication year - 2014
Publication title -
journal of cancer research and practice
Language(s) - English
Resource type - Journals
eISSN - 2589-0425
pISSN - 2311-3006
DOI - 10.1016/s2311-3006(16)30027-1
Subject(s) - medicine , prostate cancer , prostate , lymph node biopsy , pathology , lymph node , adenocarcinoma , biopsy , cancer , generalized lymphadenopathy , lymphoma , prostate specific antigen , oncology
Prostate cancer typically metastasizes to bones and regional lymph nodes. Generalized lymphadenopathy is a rare manifestation of metastatic prostate cancer. We report a case of prostate cancer in a 65-year-old male with initial presentation of generalized lymphadenopathy and no urinary symptoms. Lymph node biopsy revealed metastatic adenocarcinoma, and immunohistochemical staining was positive for prostate-specific antigen (PSA) compatible with a prostatic origin. Directed biopsy confirmed that the tumor originated in the prostate. Therefore, the prostate should be considered a possible origin of metastatic adenocarcinoma in men, and presentations consistent with generalized lymphadenopathy cannot exclude a diagnosis of prostate cancer