Open AccessMid-face location of primary basal cell carcinoma related to cancer aggressivity
Author(s) -
Prasetyadi Mawardi,
Handono Kalim,
Kusworini Handono Kalim,
Loeki Enggar Fitri,
Karyono Mintaroem,
Ambar Mudigdo,
Oyong,
Brian Wasita
Publication year - 2016
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(16)61103-9
Subject(s) - basal cell carcinoma , h&e stain , histopathological examination , medicine , biopsy , stain , pathological , carcinoma , lesion , adult male , pathology , dermatology , basal cell , staining
Objective: To study the aggressiveness of basal cell carcinoma (BCC) on the mid-face location.\udMethods: A total of 30 patients were diagnosed using specimen biopsy with hematoxylineosin stain at Moewardi Public Hospital in Surakarta, Central Java, Indonesia. The age, gender\uddistribution, site of the lesion, as well as clinic-pathological appearance were analyzed.\udResults: There were 30 patients consisting of 46.7% males and 53.3% females with ages\udranging from 33 to 91 years old and with the most common occupation, such as farmers (53.6%)\udand housewives (26.7%). Morpheaform subtypes BCC were more frequent than other types.\udBased on the predilection, most of the BCC were found to be in the mid-face (76.7%) and using\uddetermined criteria of histopathological examination, the aggressive appearance was 77% and\udnon-aggressive BCC was 23%. The BCC on the mid-face location was more aggressive than the\udother sites (P < 0.05).\udConclusions: BCC is the most common skin tumor in humans with rare metastases, which\udmight cause significant damage due to its local recurrences and aggressiveness. BCC on the\udmid-face is significantly more aggressive than that on the other predilection sites