Open AccessThe levels of Toxoplasma gondii profilin and adiponectin in obese patients complicated with or without metabolic syndrome as compared to non-obese patients
Author(s) -
Agustin Iskandar,
M. Rasjad Indra,
Satuman,
Novi Khila Firani,
Titin Andri Wihastuti
Publication year - 2016
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(15)61028-3
Subject(s) - metabolic syndrome , adiponectin , profilin , medicine , obesity , endocrinology , toxoplasma gondii , gastroenterology , insulin resistance , biology , immunology , biochemistry , antibody , actin cytoskeleton , cytoskeleton , cell
Objective: To find out the levels of Toxoplasma gondii (T. gondii) profilin and adiponectin in\udobese patients complicated with or without metabolic syndrome as compared to non-obese\udpatients.\udMethods: This study was an observational analytic study using cross sectional design. After\udinterview, the subjects were performed with a anthropometric test and then a metabolic\udsyndrome panel. The levels of profilin and adiponectin were detected by using ELISA method.\udResults: There was a significant difference of T. gondii profilin between the obese complicated\udwith metabolic syndrome group and the non-obese group (P = 0.00; α = 0.05), as well as\udthe metabolically healthy obese, in which the level of profilin was significantly higher in the\udgroup as compared to the non-obese group (P = 0.001; α = 0.05). Adiponectin level of the\udobese complicated with metabolic syndrome group was significantly lower as compared to the\udmetabolically healthy obese and non-obese group (P = 0.001; α = 0.05).\udConclusions: The level of T. gondii profilin in obese patients was higher than that in the nonobese, whereas the level of adiponectin in obese patients complicated with metabolic syndrome\udwas lower than that in the obese without metabolic syndrome and non-obese patients