Open AccessA systematic review of the effects of Iranian pharmaceutical plant extracts on Giardia lamblia
Author(s) -
Hajar Ziaei Hezarjaribi,
Taher Elmi,
Mohammad Saaid Dayer,
Shirzad Gholami,
Mahdi Fakhar,
Mostafa Akbariqomi,
Fatemeh Ghaffarifar
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(15)60959-8
Subject(s) - traditional medicine , phytochemical , giardia , biology , apiaceae , asteraceae , sativum , botany , medicine , microbiology and biotechnology
This study aimed to provide a systematic review regarding anti-Giardia effect of different\udIranian plant extracts used in vivo and in vitro on cysts and trophozoites. Many reports\udindicated that most of plant extracts used as anti-Giardia were obtained from Liliaceae,\udApiaceae, Asteraceae, and Myrtaceae. These extracts included different fractions such as\udaqueous, alcoholic and chloroform extracts as well as Soxhlet extraction of juice or essence.\udThe findings of this review showed that hydroalcoholic extract of asafoetida, Chenopodium\udbotrys, and chloroformic extract of feverfew (Tanacetum parthenium) have the maximum effect\ud(100% efficacy) on in vitro application against Giardia. However, the highest in vivo effect\udof 100% therapeutic significance was recorded for the extract of Allium sativum at 80 mg/mL\udconcentration. Given the plant species richness of Iran in terms of herbal medicines with fewer\udside effects, it can be a good alternative to chemical drugs used to treat giardiasis