Vitamin D plus calcium supplementation increased serum 25(OH)D on reproductive age women workers

Objective: To analyze the efficacy of calcium supplementation plus vitamin D on the improved\udconcentrations of serum 25(OH)D and the blood pressure in working women of childbearing\udage.\udMethods: The design used in this research was an experimental study (randomized control\udtrial), with 39 subjects of women at childbearing age who met the inclusion criteria for the\udstudy. Subjects were randomly allocated into two treatment groups, the VDC group (400 IU\udof vitamin D plus 500 mg of calcium) and the VD group (400 IU of vitamin D). Supplements\udwere consumed every day for 12 weeks.\udResults: Prior to supplementation, the average level of serum 25(OH)D in the VDC group was\ud(16.7 ± 4.5) ng/dL which was higher than the average level of serum 25(OH)D in the VD group\udwhich was (14.9 ± 5.1) ng/dL. After supplementation, the subjects of VDC group showed an\udaverage increased 3.6 ng/dL of serum 25(OH)D. The average increase of serum 25(OH)D in\udVD group was 6.3 ng/dL. The increase of serum 25(OH)D in VDC group was 21.6%, while in\udthe VD group the increase was almost two times higher (42.3%) than that of the VDC group.\udStatistical test results showed that the average levels of serum 25(OH)D between the two\udtreatment groups were significantly different.\udConclusions: The average systolic blood pressure prior to supplementation of the VDC group\udwas (128.5 ± 22.5) mmHg which was slightly lower than that of the VD group [(131.1 ± 18.0)\udmmHg]