Open AccessAntibacterial activity of combined medicinal plants extract against multiple drug resistant strains
Author(s) -
Rafiqul Islam,
Md. Shahedur Rahman,
Riad Hossain,
Nazmun Nahar,
Belal Hossin,
Abir Ahad,
Shaikh Mizanur Rahman
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(15)60878-7
Subject(s) - klebsiella pneumoniae , proteus vulgaris , antibacterial activity , microbiology and biotechnology , agar diffusion test , antibiotics , traditional medicine , biology , klebsiella pneumonia , klebsiella , bacillus subtilis , escherichia coli , proteus , pseudomonas aeruginosa , bacteria , medicine , biochemistry , genetics , gene
Objective: To find out the combined antibacterial efficacy of Aegle marmelos, Aphanamixis\udpolystachya, Cuscuta reflexa and Aesclynomene indica against bacterial pathogens.\udMethods: Antibacterial potency of combined plant extracts has been tested against Bacillus\udsubtilis IFO 3026, Sarcina lutea IFO 3232, Xanthomonas campestris IAM 1671, Escherichia coli\udIFO 3007, Klebsiella pneumoniae ATTC 10031, Proteus vulgaris MTCC 321 and Pseudomonas\uddenitrificans KACC 32026 by disc diffusion assay. Commercially available standard antibiotic\uddiscs were also used to find out antibiotic resistance pattern of test organisms.\udResults: Among the test organisms, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae\udand Proteus denitrificans showed resistance against multiple commercially available\udantibiotics. On the other hand, these multiple drug resistant organisms showed susceptibility\udagainst combined plant extracts.\udConclusions: These combined plants extracts showed synergistic antibacterial activity and\udcould lead to new antibacterial drug designing