Open AccessStudy on total phenolics and antioxidant activity of leaves crude extracts of Annona squamosa traditionally used for the treatment of cancerous tumours
Author(s) -
Aziza Saif Rashid Alkhawalidy,
M. Amzad Hossain
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(15)60876-3
Subject(s) - annona squamosa , antioxidant , traditional medicine , chemistry , annona , botany , annonaceae , biology , medicine , biochemistry
Objective: To use the leaves of Annona squamosa (A. squamosa) for the preparation of\udcrude extracts and all crude extracts were used to evaluate their antioxidant activity and total\udphenolics content collected from Jabal Al Akhdar.\udMethods: The leaves powder samples of A. squamosa were used for the preparation of crude\udextracts with methanol by Soxhlet extractor method. Defatted methanol crude extract by water\udwas extracted by different polarities of solvents with increasing polarities. All crude extracts\udwere used for the determination of total phenolics content and antioxidant activity by FolinCiocalteu reagent and 2,2-diphenyl-1-picrylhydrazyl methods.\udResults: The high amount of total phenolics content found in the leaves crude extracts was in\udthe range of 54.75 to 352.0 mg/100 g of dry powder samples. The highest antioxidant activity\udwas found in methanol and the lowest was found in ethyl acetate crude extract.\udConclusions: The crude extracts from A. squamosa leaves showed strong antioxidant activity.\udTherefore, it could be used as a medicine for the treatment food borne diseases