Open AccessPrevalence and antibiotic susceptibility pattern of fluoroquinolone resistant Shigella species isolated from infants stool in Gulbarga district, Karnataka, India
Author(s) -
. Prabhurajeshwar,
Ajay Kumar Oli,
C Ashajyothi,
R. Kelmani Chandrakanth
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(15)60871-4
Subject(s) - shigella , antibiotics , veterinary medicine , microbiology and biotechnology , biology , medicine , bacteria , salmonella , genetics
Objective: To resolve the incidence rate of Shigella species and emergence of multiple drug\udresistance to cephalosporins and fluoroquinolones generation drugs in Gulbarga district and\udnearby area is a matter of concern for the better management of Shigellosis in children.\udMethods: The study work involved all infants with acute diarrhoea, ranging 1 month to 5\udyears of age. Total 334 stool samples were collected during 2013-2014. Incidence, phenotypic\udand genotypic (16S rRNA) characteristics and antimicrobial resistance were determined for\udemerging antibiotics against Shigella strains were studied.\udResults: Total 43 (12.87%) positive Shigella species retrieved from 334 stool samples, Shigella\uddysentriae (48.83%), Shigella flexneri (32.55%) were the predominant, followed by Shigella\udsonnei (18.60%) and no case of Shigella boydii (0%). Among the Shigella isolates 32 (74.41%)\udwere MDR strains, confer the high resistance rate like 100%, 95.33%, 87.5% and 85% to\uddifferent class of antibiotics studied.\udConclusions: This study illustrates the appearance of the results of long-term supervision and\udantimicrobial resistance in clinical Shigella strains. Data collected as part of the examination\udwill be involved for developing treatment, allocate for the community and to present control\udreport with which to discriminate outbreak strains in the future