Open AccessA comparison of the antimicrobial effectiveness of different polarities crude extracts from the leaves of Adenium obesum used in Omani traditional medicine for the treatment of microbial infections
Author(s) -
M. Amzad Hossain,
Amira Hamood Salim Al-Musalami,
Mohammad Sohail Akhtar,
Sadri A. Said
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60761-1
Subject(s) - antimicrobial , traditional medicine , gram , chemistry , potency , solvent , chromatography , antibiotics , methanol , extraction (chemistry) , biology , bacteria , medicine , in vitro , biochemistry , organic chemistry , genetics
Objective: To study and compare different crude extracts from the leaves of Adenium obesum for\udantimicrobial potency and to perform different group tests.\udMethods: After processed, the leaves samples were used for extraction with methanol solvent\udby Soxhlet extraction method. The methanol crude extract was prepared by evaporating the\udsolvent. The obtained extract was defatted by water and fractioned into different solvents. All\udthe fractionated crude extracts were evaporated and used for antimicrobial study by disc method\udagainst pathogenic bacterial strains (Gram-positive and Gram-negative). The antimicrobial\udresults for all crude extracts obtained from the leaves of Adenium obesum were compared with a\udstandard antibiotic amoxicillin.\udResults: The calculated diameter of inhibition zone for all polarities crude extracts were in\udthe range of 0-13 mm. The results showed that all crude extracts have strong potential against\uddifferent pathogenic bacterial strains.\udConclusions: The isolated crude extracts by Soxhlet method could be used as herbal or\udpharmaceutical medicine for the treatment of infectious diseases