Open AccessMutagenic and antimutagenic activities of Artemisia absinthium volatile oil by the bacterial reverse mutation assay in Salmonella typhimurium strains TA98 and TA100
Author(s) -
Mahboubeh Taherkhani
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60739-8
Subject(s) - salmonella , essential oil , food science , chemistry , mutagenesis , bacteria , microbiology and biotechnology , biology , mutation , biochemistry , gene , genetics
Objective: To investigate the mutagenic and antimutagenic activities of Artemisia absinthium L.\ud(A. absinthium) essential oil by the bacterial reverse mutation assay in Salmonella typhimurium (S.\udtyphimurium) strains.\udMethods: Water-distilled essential oil of A. absinthium collected from Ardabil, NorthWestern Iran, was investigated for mutagenic and antimutagenic activities. In present study, the\udmutagenic and antimutagenic activities of A. absinthium oil were investigated by the bacterial\udrevere mutation assay in S. typhimurium TA98 and TA100 strains with and without S9 (microsomal\udmutagenesis assay).\udResults: The comparative mutagenicity effect was seen in 1.5 mg/plate by the bacterial reverse\udmutation assay in S. typhimurium TA98 strains, without S9 and the excellent antimutagenicity\udeffect was seen in 1.5 mg/plate against S. typhimurium TA100, without S9.\udConclusions: The mutagenicity and antimutagenicity effects of the volatile oil of A. absinthium\udwere seen without the presence of metabolic activation