Open AccessAssessment of vertical dengue virus transmission in Aedes aegypti and serotype prevalence in Bantul, Indonesia
Author(s) -
Tri Baskoro Tunggul Satoto,
Siti Rahmah Umniyati,
Fardhiasih Dwi Astuti,
Nastiti Wijayanti,
Laurent Gavotte,
Christian Devaux,
Roger Frutos
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60677-0
Subject(s) - dengue virus , dengue fever , aedes aegypti , serotype , transmission (telecommunications) , outbreak , virology , biology , aedes , environmental health , medicine , ecology , larva , electrical engineering , engineering
Objective: To determine the reality of dengue virus (DENV) serotype circulation in Bantul and the\udpotential impact of a vertical transmission in the maintenance of dengue.\udMethods: Mosquitoes were captured using ovitraps in the vicinity of households of patients\uddiagnosed with severe forms of dengue. DENV was detected in mosquitoes by immunochemistry\udand typed by reverse transcription-polymerase chain reaction.\udResults: Aedes aegypti mosquitoes infected with DENV were found in 14 out of 17 districts in the\udBantul Regency. Vertical transmission was demonstrated and serotype prevalence was coherent\udwith the current clinical situation and the previous reports. DENV-3 was the most common\udserotype (12 districts), followed by DENV-2 (3 districts) and DENV-4 (1 district). No DENV-1 was\udfound.\udConclusions: Unlike continental countries such as Cambodia or Thailand, where the replacement\udof serotypes is the rule, maintenance of DENV-3 is a major feature in Java. Vertical transmission\udis likely to play a major role along with the archipelago structure of Indonesia, which might help\udmaintaining local mosquito populations. Regular survey of circulating DENV and prevalence will\udhelp predicting and controlling outbreaks