Open AccessAn epidemiological study on the drug resistance of Escherichia coli strains isolated from women patients with urinary tract infection in Shalamzar, Iran
Author(s) -
Gholamreza Farnoosh,
Mohamadreza Mahmoudian Sani,
Kazem Hassanpour,
Mostafa Mellat,
Ramezan Ali Taheri
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60662-9
Subject(s) - nitrofurantoin , ciprofloxacin , klebsiella pneumonia , microbiology and biotechnology , escherichia coli , trimethoprim , antibiotics , medicine , sulfamethoxazole , drug resistance , urinary system , antibiotic sensitivity , urine , biology , biochemistry , gene
Objective: To investigate drug resistance of various strains of Escherichia coli (E. coli) bacteria\udisolated from female patients with urinary tracts infections (UTIs) in Shalamzar, Iran.\udMethods: This study was conducted from April 2011 to April 2012 on 150 female patients with\udpositive urine culture and 105 CFU/mL colony count. The pattern of antibiotic sensitivity was\udrecognized using antibiogram by the disc diffusion method.\udResults: The results revealed that the predominant bacterium was E. coli (90%), followed by\udKlebsiella pneumonia (3%). Trimethoprim-sulfamethoxazole is the initial medicine to treat UTIs\ud(without complications) which demonstrated relatively poor activity against E. coli (with 40%\udsensitivity), though alternative medicines such as nitrofurantoin (97% sensitivity) and ciprofloxacin\ud(91% sensitivity) showed good activity against E. coli as well.\udConclusions: The findings emphasized the necessity of pursuing the investigations in national\udand local governments in order to retain the efficacy of treating UTIs using effective antibiotics