Open AccessCerebral malaria: susceptibility weighted MRI
Author(s) -
Vinit Baliyan,
Jeyaseelan Nadarajah,
Atin Kumar,
Zohra Ahmad
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60661-7
Subject(s) - cerebral malaria , susceptibility weighted imaging , microangiopathy , malaria , medicine , pathology , plasmodium falciparum , magnetic resonance imaging , parenchyma , radiology , diabetes mellitus , endocrinology
Cerebral malaria is one of the fatal complications of Plasmodium falciparum infection.\udPathogenesis involves cerebral microangiopathy related to microvascular plugging by infected\udred blood cells. Conventional imaging with MRI and CT do not reveal anything specific in case of\udcerebral malaria. Susceptibility weighted imaging, a recent advance in the MRI, is very sensitive\udto microbleeds related to microangiopathy. Histopathological studies in cerebral malaria have\udrevealed microbleeds in brain parenchyma secondary to microangiopathy. Susceptibility weighted\udimaging, being exquisitely sensitive to microbleeds may provide additional information and\udimprove the diagnostic accuracy of MRI in cerebral malaria