Open AccessPhytochemical screening and antioxidant activity of different solvent extracts from Strychnos minor Dennst leaves
Author(s) -
K.M. Maria John,
Muniappan Ayyanar,
T. Arumugam,
Gansukh Enkhtaivan,
Kijoun Jin,
Doo Hwan Kim
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60654-x
Subject(s) - phytochemical , chemistry , antioxidant , polyphenol , traditional medicine , terpenoid , botany , biology , organic chemistry , biochemistry , medicine
Objective: To study the phytochemical class and its antioxidant activity of various extractions of\udStrychnos minor (S. minor), a rare endemic medicinal plant of South India.\udMethods: Leaves of S. minor were collected from Agasthiyar Malai hills of South India and shade\uddried. Different solvent extractions were made for the preliminary screening of phytochemicals\udand their total flavonoids and polyphenols levels were quantified using standard procedures.\udFinally, the extracts were studied for their antioxidant potential by 1,1-diphenyl-2-picrylhydrazyl\udand chelating effects on ferrous ions.\udResults: Phytochemical screening of the plant shows the presence of various biochemicals like\udalkaloid, tannins, terpenoids, saponins, flavonoids and resins and absence of phlobatannins.\udFlavanoids were high with water extracts (6.1 4 mg/g) and showed high 1,1-diphenyl-2-\udpicrylhydrazyl radical scavenging activity (77.25%) whereas total polyphenols was high with\udmethanol extraction (12.12 mg/g). Ethylacetae extract showed poor flavanoid and polyphenol\udcontent which reflected their low antioxidant potential when compared to other extracts.\udConclusions: The present study confirms the presence of various phytochemicals which shows\udgood antioxidant potential of S. minor. This work will be helpful to explore the biochemical\udprofile and active compound identification in the field of pharmaceutical research