Open AccessMonograph: In vitro efficacy of 30 ethnomedicinal plants used by Indian aborigines against 6 multidrug resistant Gram-positive pathogenic bacteria
Author(s) -
Mahesh Chandra Sahu,
Debasmita Dubey,
Shakti Rath,
Tribhuban Panda,
Rabindra N. Padhy
Publication year - 2015
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60641-1
Subject(s) - traditional medicine , murraya , medicinal plants , antibacterial activity , agar diffusion test , cassia , biology , minimum inhibitory concentration , glycoside , antimicrobial , phytochemical , chemistry , bacteria , botany , microbiology and biotechnology , medicine , genetics , alternative medicine , traditional chinese medicine , pathology
Objective: To monitor in vitro antibacterial activities of leaf extracts of 30 common and noncommon plants used by aborigines in Kalahandi district, Odisha, against 6 clinically isolated\udmultidrug resistant (MDR) Gram-positive bacteria of 3 genera, Staphylococcus, Streptococcus, and\udEnterococcus.\udMethods: The antibiotic sensitivity patterns of 6 bacterial strains were studied with the diskdiffusion method with 1 7 antibiotics belonging to 8 classes. Monitored plants have ethnomedicinal use and several are used as traditional medicines. Antibacterial properties were\udstudied with the agar-well diffusion method. Minimum inhibitory concentration and minimum\udbactericidal concentration values of ethanolic and aqueous extracts of plants were determined by\udthe microbroth-dilution method.\udResults: Ethanolic plant-extracts had the better antibacterial potencies in comparison to\udtheir corresponding aqueous extracts. Plants with most conspicuous antibacterial properties in\udcontrolling MDR strains of Gram-positive bacteria were aqueous and ethanolic extracts of plants,\udIxora coccinea, Nyctanthes arbor-tristis, Polycythaemia rubra, Pongamia pinnata and Syzygium\udcumini, Carthamus tinctorius, Cucurbita maxima, Murraya koenigii, Leucas aspera, Plumbago\udindica and Psidium guajava. Ethanolic extracts of most plants had phytochemicals, alkaloids,\udglycosides, terpenoids, reducing sugars, saponins, tannins, flavonoids and steroids.\udConclusions: These plants could be used further for the isolation of pure compounds to be used\udas complementary non-microbial antimicrobial medicines