Open AccessEvaluation of usefulness of pleural fluid adenosine deaminase in diagnosing tuberculous pleural effusion from empyema
Author(s) -
Vijetha Shenoy Belle,
Kriti Singh,
Krishnananda Prabhu,
P. C. Datta,
BS Varashree
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60479-5
Subject(s) - adenosine deaminase , medicine , empyema , pleural effusion , pleural fluid , effusion , gastroenterology , tuberculosis , adenosine , pathology , surgery
Objective: To evaluate the utility of adenosine deaminase activity in the pleural fluid for the\uddiagnosis of tuberculous pleural effusion from empyema of non-tubercular origin.\udMethod: A retrospective analysis of data was performed on patients who were diagnosed to\udhave tuberculous pleural effusion and empyema of non tubercular origin. Among 46 patients\udat Kasturba Hospital, Manipal University, Manipal, Karnataka, India, from November 201 2\udto February 2013 who underwent pleural fluid adenosine deaminase estimation, 25 patients\udwith tuberculous pleural effusion and 21 patients with empyema were diagnosed respectively.\udAdenosine deaminase in pleural fluid is estimated using colorimetric, Galanti and Guisti method.\udResults: Pleural fluid Adenosine Deaminase levels among tuberculous pleural effusion(109.38依\ud53.83 ), empyema (141.20依71.69 ) with P=0.27.\udConclusion: Pleural fluid adenosine deaminase alone cannot be used as a marker for the\uddiagnosis of tuberculous pleural effusion