Open AccessDetection of Mycoplasma pneumoniae and Chlamydia trachomatis in Iranian children with acute lower respiratory infections by polymerase chain reaction
Author(s) -
Mostafa Behpour Oskooee,
Abdollah Karimi,
Farideh Shiva,
Fatemeh Fallah,
Sedigheh Rafiei Tabatabaei,
Fariba Shirvani,
Ahmad Reza Shamshiri,
Saadat Adabian,
Mohammad Rahbar
Publication year - 2014
Publication title -
asian pacific journal of tropical disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 33
ISSN - 2222-1808
DOI - 10.1016/s2222-1808(14)60460-6
Subject(s) - mycoplasma pneumoniae , chlamydia trachomatis , medicine , chlamydia , polymerase chain reaction , pneumonia , pediatrics , population , chlamydophila pneumoniae , immunology , chlamydiaceae , biology , environmental health , biochemistry , gene
Objective: To determine the frequency of Mycoplasma pneumoniae (M. pneumoniae) and\udChlamydia trachomatis (C. trachomatis) in young children with community acquired pneumonia\ud(CAP) and detect C. trachomatis in the subgroup of infants under 1 year of age in Tehran, Iran.\udMethods: This cross-sectional study was designed to detect M. pneumoniae from all children (<5\udyears of age) presenting with CAP, admitted to a tertiary care children ’s hospital affiliated with\udthe Shaheed Beheshti University of Medical Sciences in Tehran during a period of 14 months, from\udNovember 2010 to December 2011. Nasopharyngeal and oropharyngeal swabs were collected from\ud102 children during the study period. Pathogens were detected using polymerase chain reaction\udand confirmed with real-time polymerase chain reaction.\udResults: Only one case of M. pneumoniae was isolated from 102 children (1%). C. trachomatis was\udnot detected in any of the 69 infants (<1 year of age).\udConclusions: According to our findings, M. pneumoniae is an uncommon cause of CAP in\udchildren under 5 years old and C. trachomatis could not be listed as causing CAP in infants in\udour study population. However, more studies with a larger sample size are needed to confirm this\udobservation